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Management Services and Administrative Agreement

Entities:
Date:
2003
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20K
ID:
#171161

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                MANAGEMENT SERVICES AND ADMINISTRATIVE AGREEMENT

     This MANAGEMENT SERVICES AND ADMINISTRATIVE AGREEMENT (this "Agreement") is
made effective as of the 1st day of April 2003 (the  "Effective  Date"),  by and
between  BioDelivery  Science   International,   Inc.,  a  Delaware  corporation
("BDSI"),  and Bioral  Nutrient  Delivery,  LLC, a  Delaware  limited  liability
company ("BND").

     WHEREAS, BND has been formed to develop a technological means of delivering
nutrients for the use and/or sale in the processed food and beverage industries;
and

     WHEREAS,  BDSI and BND desire to set forth in this Agreement  certain terms
and  conditions  relating to  services  to be  performed  by BDSI  (through  its
employees) for BND (collectively, the "Services").

     NOW,  THEREFORE,  in  consideration of the mutual promises and undertakings
set forth below, and for other good and valuable consideration,  the receipt and
sufficiency of which is hereby  acknowledge  by the parties,  the parties hereto
agree as follows:

     1. Term;  Termination.  The term of this  Agreement  shall  begin as of the
Effective Date and, unless sooner terminated in accordance with subsections (a),
(b) or (c) of this  Section 1 or any other  provision of this  Agreement,  shall
continue  until April 1, 2004 (such term,  the "Initial  Term").  This Agreement
will terminate at the conclusion of the Initial Term. At such time, BDSI and BND
will  evaluate  the need for  continuation  of the  provision of the Services by
BDSI.

     Notwithstanding the foregoing, this Agreement may be terminated at any time
in the following circumstances:

     (a) BDSI, in its sole and absolute discretion,  may at any time cancel this
Agreement upon thirty (30) days prior written notice to BND;

     (b) If either party commits a material breach of this  Agreement,  and such
material  breach is either not  curable or is curable  but  remains  uncured for
thirty (30) days after written  notice of such  material  breach is delivered to
the breaching party, then the non-breaching party may immediately terminate this
Agreement  by  providing  the  breaching  party  with  written  notice  of  such
termination.  The right of  termination  provided  in this  Section  1(b) is not
exclusive of any remedies to which either party may otherwise be entitled at law
or in equity in the event of a breach of this Agreement.

     (c) In the event that either  party  hereto (i) becomes  insolvent or shall
cease to pay its debts  when due;  or (ii) is found  bankrupt  by any  judicial,
administrative  or  other  appropriate  agency  having   jurisdiction,   whether
voluntary  or  involuntary,  and  such  insolvency  is  not  corrected  or  such
bankruptcy  declaration is not vacated  within thirty (30) days,  then the other
party shall have the right to immediately  terminate this Agreement by providing


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